Search on: OMEGA-AGATOXIN IVA 
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Descriptor English:   omega-Agatoxin IVA 
Descriptor Spanish:   omega-Agatoxina IVA 
Descriptor Portuguese:   omega-Agatoxina IVA 
Synonyms English:   omega-Aga-IVA  
Tree Number:   D12.776.466.693
D20.888.065.870.650
D23.946.833.065.870.650
Definition English:   A neuropeptide toxin from the venom of the funnel web spider, Agelenopsis aperta. It inhibits CALCIUM CHANNELS, P-TYPE by altering the voltage-dependent gating so that very large depolarizations are needed for channel opening. It also inhibits CALCIUM CHANNELS, Q-TYPE. 
Pharmacological Action:   Calcium Channel Blockers
Neurotoxins
 
History Note English:   2000; use OMEGA-AGATOXIN IVA (NM) 1992-1999 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
pharmacokinetics poisoning
radiation effects secretion
toxicity therapeutic use
urine  
Record Number:   34517 
Unique Identifier:   D020867 

Occurrence in VHL:
 

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